Brief Information of the Compound and Protein
Compound Name
 Compound Info 
LK-204-545
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 PubChem ID
CID: 5311116
SID: 15406259
Canonical SMILES
OC(CNCCNC(=O)Nc1ccc(O)cc1)COc1ccc(OCCOCC2CC2)cc1C#N
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Compound Formula C25H32N4O6
Compound Structure
Protein Name
 Protein Info 
Beta-1 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P18090
Gene Name
ADRB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  5
1
Ki = 7.943 nM
   TI
   LI
   LO
   TS
2
Ki = 63.1 nM
   TI
   LI
   LO
   TS
3
Ki = 79.43 nM
   TI
   LI
   LO
   TS
4
Ki = 100 nM
   TI
   LI
   LO
   TS
5
Ki = 79432.82 nM
   TI
   LI
   LO
   TS