Brief Information of the Compound and Protein
Compound Name
3-(5-fluoro-1H-indol-3-yl)-N-(2-quinoxalin-5-yloxyethyl)propan-1-amine
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PubChem ID
CID: 11394411
SID: 16489188
Canonical SMILES
Fc1ccc2[nH]cc(CCCNCCOc3cccc4nccnc34)c2c1
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Compound Formula C21H21FN4O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
EC50 = 13.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 46 nM
   TI
   LI
   LO
   TS
3
Ki = 9.8 nM
   TI
   LI
   LO
   TS