Brief Information of the Compound and Protein
Compound Name
N-[2-[(7-fluoro-2,3-dihydro-1,4-benzodioxin-5-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine
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PubChem ID
CID: 11303781
SID: 16392229
Canonical SMILES
Fc1ccc2[nH]cc(CCCNCCOc3cc(F)cc4OCCOc34)c2c1
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Compound Formula C21H22F2N2O3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 156 nM
   TI
   LI
   LO
   TS
2
IC50 = 198 nM
   TI
   LI
   LO
   TS
3
Ki = 22.4 nM
   TI
   LI
   LO
   TS