Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-(1H-benzimidazol-4-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine
    Show/Hide
 PubChem ID
CID: 9798593
SID: 14754319
Canonical SMILES
Fc1ccc2[nH]cc(CCCNCCOc3cccc4nc[nH]c34)c2c1
    Show/Hide
Compound Formula C20H21FN4O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 1.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 7.2 nM
   TI
   LI
   LO
   TS
3
Ki = 0.69 nM
   TI
   LI
   LO
   TS