Brief Information of the Compound and Protein
Compound Name
(S)-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)-6-methyl-3-(2-(methylamino)-3-phenylpropyl)pyrimidine-2,4(1H,3H)-dione
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PubChem ID
CID: 9984259
SID: 14962284
Canonical SMILES
CN[C@@H](Cc1ccccc1)Cn1c(=O)c(c(C)n(Cc2c(F)cccc2F)c1=O)-c1cccc(OC)c1F
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Compound Formula C29H28F3N3O3
Compound Structure
Protein Name
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 8.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM
2 Ki = 8.1 nM
3 Ki = 200 nM