Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
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 PubChem ID
CID: 3045227
SID: 15196110
Canonical SMILES
C[C@H](N)Cn1ccc2cc(F)c(Cl)cc12
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Compound Formula C11H12ClFN2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 131 nM
   TI
   LI
   LO
   TS
2
EC50 = 400 nM
   TI
   LI
   LO
   TS
3
Ki = 39 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 50.12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 31.62 nM
2 Ki = 38 nM