Brief Information of the Compound and Protein
Compound Name
3-(4-{2-[(R)-4-(4-fluoro-benzyl)-2-methyl-piperazin-1-yl]-2-oxo-ethoxy}-biphenyl-3-ylamino)-4-methylamino-cyclobut-3-ene-1,2-dione
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PubChem ID
CID: 44430727
Canonical SMILES
CNc1c(Nc2cc(ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)-c2ccccc2)c(=O)c1=O
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Compound Formula C31H31FN4O4
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS