Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 17
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 PubChem ID
CID: 44176199
Canonical SMILES
OC(=O)CCCCN1c2ccc(I)cc2C(=O)N(Cc2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)C1=O
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Compound Formula C27H23Cl2IN2O4
Compound Structure
Protein Name
 Protein Info 
E3 ubiquitin-protein ligase Mdm2
Protein Classification
Other nuclear protein
Uniprot ID
Q00987
Gene Name
MDM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
CL000111 MDA-MB-231
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 60000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8220 nM