Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
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 PubChem ID
CID: 2733484
SID: 14755701
Canonical SMILES
Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1
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Compound Formula C19H21ClN2O2S
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 2511.89 nM
   TI
   LI
   LO
   TS
2
IC50 = 56.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 100 nM
   TI
   LI
   LO
   TS
4
Ki = 120 nM
   TI
   LI
   LO
   TS
CL000058 T-REx-293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 74 nM
2 IC50 = 2600 nM