Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2E)-3-[16-(hydroxymethyl)-5-oxo-4,14,18-triazaheptacyclo[12.10.2.0^{2,6}.0^{7,26}.0^{8,13}.0^{18,25}.0^{19,24}]hexacosa-1(25),2(6),7(26),8(13),9,11,19,21,23-nonaen-10-yl]prop-2-enoic acid
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 PubChem ID
CID: 44430914
Canonical SMILES
OCC1Cn2c3ccccc3c3c4CNC(=O)c4c4c5cc(\C=C\C(O)=O)ccc5n(C1)c4c23
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Compound Formula C27H21N3O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK3
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P52333
Gene Name
JAK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 686 nM
   TI
   LI
   LO
   TS