Brief Information of the Compound and Protein
Compound Name
(1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-chloro-1Hindazol-3-yl)amine
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PubChem ID
CID: 11653882
SID: 16757404
Canonical SMILES
Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1
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Compound Formula C20H21ClN4O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000863 I3.4.2 Homo sapiens (Human)  1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32 Homo sapiens (Human)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 260 nM
   TI
   LI
   LO
   TS