Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3-chloro-4-fluorophenyl)-1-[(1R,3R)-3-(3-cyanophenyl)cyclopentyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
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 PubChem ID
CID: 11648976
SID: 16752367
Canonical SMILES
CN1CCN(CCCN([C@@H]2CC[C@H](C2)c2cccc(c2)C#N)C(=O)Nc2ccc(F)c(Cl)c2)CC1
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Compound Formula C27H33ClFN5O
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 161 nM
   TI
   LI
   LO
   TS