Brief Information of the Compound and Protein
Compound Name
1-[(1R,2S,5R)-5-(3-cyanophenyl)-2-bicyclo[3.1.0]hexanyl]-3-(3,5-dichlorophenyl)-1-(2-pyrrolidin-1-ylethyl)urea
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PubChem ID
CID: 44409479
Canonical SMILES
Clc1cc(Cl)cc(NC(=O)N(CCN2CCCC2)[C@H]2CC[C@]3(C[C@@H]23)c2cccc(c2)C#N)c1
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Compound Formula C26H28Cl2N4O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 15 nM
   TI
   LI
   LO
   TS