Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,4-diaminopyrimidine derivative, 8j
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 PubChem ID
CID: 11453509
SID: 16552561
Canonical SMILES
COc1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1
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Compound Formula C26H27N5O2
Compound Structure
Protein Name
 Protein Info 
Growth hormone secretagogue receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
GRP-related receptor
Uniprot ID
Q92847
Gene Name
GHSR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 7.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 90 nM
   TI
   LI
   LO
   TS