Brief Information of the Compound and Protein
Compound Name
(S)-6-bromo-9a-(2-cyclopropyl-ethyl)-8,9,9a,10-tetrahydro-3H-2,3-diaza-cyclopenta[a]fluoren-7-one
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PubChem ID
CID: 44414066
Canonical SMILES
BrC1=C2c3ccc4[nH]ncc4c3C[C@]2(CCC2CC2)CCC1=O
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Compound Formula C19H19BrN2O
Compound Structure
Protein Name
Estrogen receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.6 nM