Brief Information of the Compound and Protein
Compound Name
(R)-4-chloro-N-(quinuclidin-3-yl)benzamide
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PubChem ID
CID: 9795278
SID: 14799085
Canonical SMILES
Clc1ccc(cc1)C(=O)N[C@H]1CN2CCC1CC2
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Compound Formula C14H17ClN2O
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000022 SH-EP1 Homo sapiens (Human)  1
1
EC50 = 128 nM
   TI
   LI
   LO
   TS
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
Ki = 24.55 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 26 nM