Brief Information of the Compound and Protein
Compound Name
4-Oxopyrimidine, 22
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PubChem ID
CID: 16747961
SID: 26734018
Canonical SMILES
CC(=O)Nc1ccc2cccc(Oc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)c2n1
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Compound Formula C22H15F3N4O2
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
2
IC50 = 77 nM
   TI
   LI
   LO
   TS