Brief Information of the Compound and Protein
Compound Name
(Z)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime
    Show/Hide
PubChem ID
CID: 11849821
SID: 17162568
Canonical SMILES
CO\N=C(/C(O)CN1CCN(CC1)c1ccccn1)c1ccc(Cl)cc1
    Show/Hide
Compound Formula C19H23ClN4O2
Compound Structure
Protein Name
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 22.6 nM
   TI
   LI
   LO
   TS
2
Ki = 150 nM
   TI
   LI
   LO
   TS