Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[5-tert-Butyl-2-(6-methoxypyridin-3-yl)-2H-pyrazol-3-yl]-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea
    Show/Hide
 PubChem ID
CID: 10165915
SID: 15159072
Canonical SMILES
COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C
    Show/Hide
Compound Formula C30H36N6O4
Compound Structure
Protein Name
 Protein Info 
Tumor necrosis factor
Protein Classification
Secreted protein
Uniprot ID
P01375
Gene Name
TNF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 42 nM
   TI
   LI
   LO
   TS