Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-Cyclopropyl-1-{3-(3,4-dichloro-phenyl)-3-[2-(3-morpholin-4-yl-azetidin-1-yl)-ethyl]-pyrrolidin-1-yl}-ethanone
    Show/Hide
 PubChem ID
CID: 44310284
Canonical SMILES
Clc1ccc(cc1Cl)C1(CCN2CC(C2)N2CCOCC2)CCN(C1)C(=O)CC1CC1
    Show/Hide
Compound Formula C24H33Cl2N3O2
Compound Structure
Protein Name
 Protein Info 
Substance-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P21452
Gene Name
TACR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS