Brief Information of the Compound and Protein
Compound Name
6-alkyl, 7-amino-2-quinolinone, 11d (+/-)
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PubChem ID
CID: 22279130
Canonical SMILES
CCC(C)c1cc2c(cc(=O)[nH]c2cc1N)C(F)(F)F
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Compound Formula C14H15F3N2O
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  3
1
EC50 = 65 nM
   TI
   LI
   LO
   TS
2
IC50 = 14 nM
   TI
   LI
   LO
   TS
3
Ki = 13 nM
   TI
   LI
   LO
   TS