Brief Information of the Compound and Protein
Compound Name
6-[(2,2,3,3,3-pentafluoropropyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one
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PubChem ID
CID: 9841791
SID: 14803397
Canonical SMILES
FC(F)(F)c1cc(=O)[nH]c2ccc(NCC(F)(F)C(F)(F)F)cc12
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Compound Formula C13H8F8N2O
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  3
1
EC50 = 246 nM
   TI
   LI
   LO
   TS
2
IC50 = 17 nM
   TI
   LI
   LO
   TS
3
Ki = 78 nM
   TI
   LI
   LO
   TS