Brief Information of the Compound and Protein
Compound Name
3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)-4-(2-hydroxy-2-(3-(trifluoromethyl)phenyl)ethylamino)pyridin-2(1H)-one
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PubChem ID
CID: 135681810
Canonical SMILES
Cc1cc(cc2nc([nH]c12)-c1c(NCC(O)c2cccc(c2)C(F)(F)F)cc[nH]c1=O)-n1ccnc1
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Compound Formula C25H21F3N6O2
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000766 SAL1 Homo sapiens (Human)  1
1
IC50 = 780 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 530 nM