Brief Information of the Compound and Protein
Compound Name
3-(2,6-Dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid [2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-phenyl]-amide
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PubChem ID
CID: 328912
Canonical SMILES
CN1CCc2ccccc2C1Cc1ccccc1NC(=O)c1c(C)onc1-c1c(Cl)cccc1Cl
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Compound Formula C28H25Cl2N3O2
Compound Structure
Protein Name
Growth hormone secretagogue receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GRP-related receptor
Uniprot ID
Q92847
Gene Name
GHSR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 980 nM