Brief Information of the Compound and Protein
Compound Name
N-(2-chloro-6-methylphenyl)-1-[6-[[4-(morpholin-4-ylmethyl)pyridin-2-yl]amino]pyrimidin-4-yl]benzimidazol-2-amine
    Show/Hide
PubChem ID
CID: 25110690
SID: 56432812
Canonical SMILES
Cc1cccc(Cl)c1Nc1nc2ccccc2n1-c1cc(Nc2cc(CN3CCOCC3)ccn2)ncn1
    Show/Hide
Compound Formula C28H27ClN8O
Compound Structure
Protein Name
Tyrosine-protein kinase Lck
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Src family
Uniprot ID
P06239
Gene Name
LCK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM