Brief Information of the Compound and Protein
Compound Name
(R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine
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PubChem ID
CID: 3022645
SID: 14850167
Canonical SMILES
CCOc1ccccc1OC(C1CNCCO1)c1ccccc1
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Compound Formula C19H23NO3
Compound Structure
Protein Name
Sodium-dependent noradrenaline transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P23975
Gene Name
SLC6A2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
2
Ki = 1.1 nM
   TI
   LI
   LO
   TS
3
Ki = 5 nM
   TI
   LI
   LO
   TS
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CL000882 MDCK-Net6 Canis lupus familiaris (Dog)  2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.2 nM
   TI
   LI
   LO
   TS