Brief Information of the Compound and Protein
Compound Name
N-[2-oxo-2-[[(3R)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-3-yl]amino]ethyl]-3-(trifluoromethyl)benzamide
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PubChem ID
CID: 44453234
Canonical SMILES
FC(F)(F)Oc1ccc(CN2CC[C@H](C2)NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)cc1
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Compound Formula C22H21F6N3O3
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 103 nM
   TI
   LI
   LO
   TS
2
IC50 = 610 nM
   TI
   LI
   LO
   TS