Brief Information of the Compound and Protein
Compound Name
(8S,11R,13S,14S)-11-[4-(6-methoxypyridin-3-yl)phenyl]-13-methylspiro[1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-17,2'-cyclopentane]-1',3-dione
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PubChem ID
CID: 44451244
Canonical SMILES
COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CCC22CCCC2=O)[C@@H]2CCC3=CC(=O)CCC3=C12
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Compound Formula C34H37NO3
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.15 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.55 nM
   TI
   LI
   LO
   TS