Brief Information of the Compound and Protein
Compound Name
(8S,11R,13S,14S,16R,17S)-11-[4-(6-chloropyridin-3-yl)phenyl]-17-(cyclopropanecarbonyl)-13,16-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
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PubChem ID
CID: 44451380
Canonical SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccc(Cl)nc1
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Compound Formula C34H36ClNO2
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.47 nM
   TI
   LI
   LO
   TS