Brief Information of the Compound and Protein
Compound Name
(8S,11R,13S,14S,16R,17S)-17-(cyclopropanecarbonyl)-11-[4-(6-methoxypyridin-3-yl)phenyl]-13,16-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
    Show/Hide
PubChem ID
CID: 44451394
Canonical SMILES
COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](C[C@@H](C)[C@@H]2C(=O)C2CC2)[C@@H]2CCC3=CC(=O)CCC3=C12
    Show/Hide
Compound Formula C35H39NO3
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.12 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.63 nM
   TI
   LI
   LO
   TS