Brief Information of the Compound and Protein
Compound Name
4-(4-chlorophenyl)-1-[1-(2-methylphenyl)sulfonylpiperidin-4-yl]piperidin-4-ol
    Show/Hide
PubChem ID
CID: 44453292
Canonical SMILES
Cc1ccccc1S(=O)(=O)N1CCC(CC1)N1CCC(O)(CC1)c1ccc(Cl)cc1
    Show/Hide
Compound Formula C23H29ClN2O3S
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
2
IC50 = 500 nM
   TI
   LI
   LO
   TS