Brief Information of the Compound and Protein
Compound Name
1-[1-(2-bromophenyl)sulfonyl-2-methylpiperidin-4-yl]-4-(4-chlorophenyl)piperidin-4-ol
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PubChem ID
CID: 44453162
Canonical SMILES
CC1CC(CCN1S(=O)(=O)c1ccccc1Br)N1CCC(O)(CC1)c1ccc(Cl)cc1
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Compound Formula C23H28BrClN2O3S
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
2
IC50 = 220 nM
   TI
   LI
   LO
   TS