Brief Information of the Compound and Protein
Compound Name
4-(4-chlorophenyl)-1-(4-methyl-1-thiophen-2-ylsulfonylpiperidin-4-yl)piperidin-4-ol
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PubChem ID
CID: 44453163
Canonical SMILES
CC1(CCN(CC1)S(=O)(=O)c1cccs1)N1CCC(O)(CC1)c1ccc(Cl)cc1
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Compound Formula C21H27ClN2O3S2
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 7330 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS