Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((3R,6S)-6-(3-(aminomethyl)phenyl)bicyclo[4.1.0]heptan-3-yl)-3-(2,6-dichloropyridin-4-yl)-1-((1-(methylsulfonyl)piperidin-4-yl)methyl)urea
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 PubChem ID
CID: 44424256
Canonical SMILES
CS(=O)(=O)N1CCC(CN([C@@H]2CC[C@@]3(CC3C2)c2cccc(CN)c2)C(=O)Nc2cc(Cl)nc(Cl)c2)CC1
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Compound Formula C27H35Cl2N5O3S
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.4 nM
   TI
   LI
   LO
   TS