Brief Information of the Compound and Protein
Compound Name
1-(3,4-Dimethoxy-benzenesulfonyl)-3-(1-methyl-pyrrolidin-3-yl)-1H-indole
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PubChem ID
CID: 10272325
SID: 15277288
Canonical SMILES
COc1ccc(cc1OC)S(=O)(=O)n1cc(C2CCN(C)C2)c2ccccc12
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Compound Formula C21H24N2O4S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 96.7 nM
   TI
   LI
   LO
   TS
2
Ki = 5 nM
   TI
   LI
   LO
   TS