Brief Information of the Compound and Protein
Compound Name
5-[3-(1-Benzyl-pyrrolidin-3-yl)-indole-1-sulfonyl]-4-methyl-thiazol-2-ylamine
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PubChem ID
CID: 10115005
SID: 15103684
Canonical SMILES
Cc1nc(N)sc1S(=O)(=O)n1cc(C2CCN(Cc3ccccc3)C2)c2ccccc12
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Compound Formula C23H24N4O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
2
Ki = 3 nM
   TI
   LI
   LO
   TS