Brief Information of the Compound and Protein
Compound Name
5'N-(3-pyridylmethyl)-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine]-5'-amine
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PubChem ID
CID: 11738788
SID: 16845127
Canonical SMILES
C(Nc1cnc2O[C@@]3(Cc2c1)CN1CCC3CC1)c1cccnc1
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Compound Formula C19H22N4O
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  1
1
Ki = 8.3 nM
   TI
   LI
   LO
   TS