Brief Information of the Compound and Protein
Compound Name
6-chloro-N-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]imidazo[2,1-b][1,3]thiazole-5-sulfonamide
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PubChem ID
CID: 10202564
SID: 15200695
Canonical SMILES
CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12
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Compound Formula C17H18ClN5O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F Homo sapiens (Human)  1
1
EC50 = 0.06457 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.58 nM
2 Ki = 2.2 nM
3 Ki = 312 nM