Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-chloro-N-[3-[2-(dimethylamino)ethyl]-2-methyl-1H-inden-5-yl]imidazo[2,1-b][1,3]thiazole-5-sulfonamide
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 PubChem ID
CID: 16112801
SID: 24759758
Canonical SMILES
CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12
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Compound Formula C19H21ClN4O2S2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 4.5 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.5 nM