Brief Information of the Compound and Protein
Compound Name
3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide
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PubChem ID
CID: 44570668
Canonical SMILES
CC12CC(=O)N(Cc3cccc(Cl)c3Cl)C1=C(CCC2)\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F
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Compound Formula C25H21Cl2F3N2O4S
Compound Structure
Protein Name
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.3 nM