Brief Information of the Compound and Protein
Compound Name
3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine
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PubChem ID
CID: 10404144
SID: 15421269
Canonical SMILES
Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
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Compound Formula C18H19ClN4
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  4
1
Ki = 2200 nM
   TI
   LI
   LO
   TS
2
Ki = 2900 nM
   TI
   LI
   LO
   TS
3
Ki = 3200 nM
   TI
   LI
   LO
   TS
4
Ki = 4300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2818.38 nM
2 Ki = 3200 nM
3 Ki = 4300 nM