Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine
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 PubChem ID
CID: 10336538
SID: 15347559
Canonical SMILES
Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
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Compound Formula C18H19ClN4
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 3400 nM
   TI
   LI
   LO
   TS
2
Ki = 6300 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 2300 nM
   TI
   LI
   LO
   TS
2
Ki = 47000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1310 nM
2 Ki = 3200 nM
3 Ki = 3388.44 nM
4 Ki = 3400 nM
5 Ki = 6300 nM
6 Ki > 6000 nM