Brief Information of the Compound and Protein
Compound Name
3-[2-(3-methylpyrrolo[1,2-a]pyrazin-1-yl)ethynyl]phenol
    Show/Hide
PubChem ID
CID: 44453455
Canonical SMILES
Cc1cn2cccc2c(n1)C#Cc1cccc(O)c1
    Show/Hide
Compound Formula C16H12N2O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 316.23 nM
   TI
   LI
   LO
   TS