Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[3-methyl-1-[2-[3-(trifluoromethyl)phenyl]ethynyl]pyrrolo[1,2-a]pyrazin-7-yl]-pyrrolidin-1-ylmethanone
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 PubChem ID
CID: 44453018
Canonical SMILES
Cc1cn2cc(cc2c(n1)C#Cc1cccc(c1)C(F)(F)F)C(=O)N1CCCC1
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Compound Formula C22H18F3N3O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 158.49 nM
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