Brief Information of the Compound and Protein
Compound Name
3-methyl-1-(2-phenylethynyl)pyrrolo[1,2-a]pyrazine-7-carbonitrile
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PubChem ID
CID: 44453348
Canonical SMILES
Cc1cn2cc(cc2c(n1)C#Cc1ccccc1)C#N
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Compound Formula C17H11N3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.259 nM
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