Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2,2-dimethylpyrrolidin-1-yl)-[3-methyl-1-(2-thiophen-3-ylethynyl)pyrrolo[1,2-a]pyrazin-7-yl]methanone
    Show/Hide
 PubChem ID
CID: 44452914
Canonical SMILES
Cc1cn2cc(cc2c(n1)C#Cc1ccsc1)C(=O)N1CCCC1(C)C
    Show/Hide
Compound Formula C21H21N3OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1258.93 nM
   TI
   LI
   LO
   TS