Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[[3-methyl-1-(2-phenylethynyl)pyrrolo[1,2-a]pyrazin-7-yl]methyl]piperazin-1-yl]ethanone
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 PubChem ID
CID: 44453420
Canonical SMILES
CC(=O)N1CCN(Cc2cc3c(nc(C)cn3c2)C#Cc2ccccc2)CC1
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Compound Formula C23H24N4O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 316.23 nM
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