Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(1R,4S)-2-azabicyclo[2.2.1]heptan-2-yl]-[3-methyl-1-(2-thiophen-3-ylethynyl)pyrrolo[1,2-a]pyrazin-7-yl]methanone
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 PubChem ID
CID: 44452917
Canonical SMILES
Cc1cn2cc(cc2c(n1)C#Cc1ccsc1)C(=O)N1C[C@H]2CC[C@@H]1C2
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Compound Formula C21H19N3OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 630.96 nM
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