Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[1-[2-(2-fluorophenyl)ethynyl]-3-methylpyrrolo[1,2-a]pyrazin-7-yl]-(4-methylpiperazin-1-yl)methanone
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 PubChem ID
CID: 44452967
Canonical SMILES
CN1CCN(CC1)C(=O)c1cc2c(nc(C)cn2c1)C#Cc1ccccc1F
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Compound Formula C22H21FN4O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1258.93 nM
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