Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1S)-1-[2-[1-[(3S,4R)-1-tert-butyl-4-[2-fluoro-4-(trifluoromethyl)phenyl]pyrrolidine-3-carbonyl]piperidin-4-yl]-5-chlorophenyl]propyl]acetamide
    Show/Hide
 PubChem ID
CID: 44448554
Canonical SMILES
CC[C@H](NC(C)=O)c1cc(Cl)ccc1C1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(cc1F)C(F)(F)F)C(C)(C)C
    Show/Hide
Compound Formula C32H40ClF4N3O2
Compound Structure
Protein Name
 Protein Info 
Melanocortin receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 88.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 22.7 nM
   TI
   LI
   LO
   TS